The gunman entered Fifth Third bank around 9 a.m. through a loading dock and opened fire in the lobby, according to police chief Eliot Isaac.
Also Thursday night, the "Cincinnati" sign on the Duke Energy Convention Center featured a special design with the colors of the city seal to honor those who were killed in the Fifth Third Bank shooting.
The motive for the shooting is unclear.
He praised police who ended the threat and the response of other emergency personnel.
If it had taken longer to kill him, Perez could have killed many more people, Mayor John Cranley said.
Police seal off the area where a gunman killed three people on Thursday.
The building the gunman targeted was said to have strict security, and it wasn't clear how he was able to get in. The University of Cincinnati Medical Center said that two victims died at the hospital and that one survivor was in critical condition and another was in serious condition.
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Thursday afternoon, the Hamilton County Sherriff executed a search warrant at the North Bend home of the suspected shooter. He said a woman wearing headphones didn't hear the warnings and walked into the bank and got shot. Leonard Cain was going back inside the bank when someone alerted him to the shooting. Another victim was located inside a nearby ice cream shop.
"There was definitely a lot of blood involved", he said.
Sammarco posted Wednesday on Facebook, asking how officials will explain to his parents "they will never see their son again because of a senseless shooting in a foreign country". He said she dropped to the ground, and everyone started running. "I went around to the north side of the building and sat down", he told The Enquirer. He said he saw a man firing a gun inside the bank lobby.
"It is all too clear that we have to do more in OH to address the gun violence affecting communities across the state", said a statement from the OH chapter of Moms Demand Action for Gun Sense.
Police do not know what why the shooter made a decision to open fire in the lobby of the skyscraper that houses the banks headquarters.
"I heard rounds of gunfire".
"My co-workers and I saw [an] injured woman lying under the flag pole with a white shirt covered in blood", said Courtney Bellish, 22.
Jaenetta Cook, who manages Servatii Bakery on the building's first floor, said she hurried to lock the door after the first two shots were fired.