Harry Kane is out of Spurs' clash with Manchester United

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It's very small and we will see for Wednesday, but tomorrow it's impossible.

Pochettino added: "We need to wait until tomorrow to decide the formation".

The England global scored twice in the 4-1 win over Liverpool last weekend at Wembley, but pulled up with a tight hamstring towards the end of the victory.

"We can't take the risk", he said. You will always missed your best striker. The England global and mooted Real Madrid target has been in blistering form this season and now tops the Premier League scoring chart with eight goals, but Pochettino confirmed that his talismanic forward will not play against Manchester United after suffering a minor hamstring injury against Liverpool on Sunday.

"It is a collective sport and always you must adapt when some player is not fit to play. It's a problem. Play more or play less, we want them available to play", Pochettino said.

"During the season some problems can happen and you have to trust all the players, all the squad".

But Argentine manager Pochettino refused to cite Kane's absence, through a hamstring injury, as a factor in the loss.

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"We can't take the risk", the Argentinian said.

"It's a decision of the doctor and medical staff not to take a risk". I told the players they are not machines and its so hard to cope with worldwide duty, play every three days.

Pochettino also said it is only a small problem but he did not want to exacerbate the issue by playing him against United.

"TEAM [email protected] underwent assessment and investigation earlier this week, which confirmed a minor strain to the left hamstring", Tottenham tweeted on Friday and gave an update on another key player.

"If not the next game, it's another one", said Guardiola, whose side have already beaten West Brom this season in the League Cup.

Mourinho will be looking for his players to show a considerable improvement on their attitude to the one they displayed against Huddersfield.

"United have one day more rest, an advantage, to prepare".