Speaking ahead of Spurs' London derby clash with West Ham United on Saturday, Pochettino made it clear that whilst he remains a keen admirer of the Belgian's talent, his injury troubles mean that it is hard for the midfielder to play week in, week out.
Spurs have lost three of their last four trips to the East London club.
Both of their wins have come away from the road, and they struggled to a 1-0 League Cup win against Barnsley at home on Tuesday.
West Ham boss Slaven Bilic will still be without playmaker Manuel Lanzini, as the Argentinian has only just returned to training following injury.
They'll need it against one of the most talented attacking sides in the world in Spurs, who will be seeking some revenge after their last visit to West Ham's new home virtually ended their title hopes for last season back in the spring.
Despite playing his final Premier League game for West Ham on January 2nd 2017, no Hammers' player has assisted (6) or created as many goalscoring chances (74) as Dimitri Payet since the start of 2016-17 in the competition.
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The striker has scored 19 goals in London derbies, and, with his annual August slow start behind him, seems nearly certain to extend that tally against West Ham.
"The global break we will have all the players away so it will be difficult to prepare and work hard to try to engage everything".
Carroll made an entrance he would prefer to forget, giving the ball away near halfway and allowing Eriksen to start the move that led to Kane's 34th-minute opener. However, Spurs seized on the home side's lack of rhythm when Andy Carroll was introduced for the injured Michail Antonio. Read on to discover the five main ways Tottenham can dominate West Ham and generate some serious momentum.
Spurs are also unbeaten in their last nine league outings in September - a record no doubt helped by Harry Kane's penchant for following up a barren August with a fruitful spell in front of goal. Aside from last weekend's blip at Swansea, Mauricio Pochettino's men appear to be rounding into form.
While they sat stony silenced after the first goal, the strike seemed to galvanise them to egg their players on some more. I have had some tough decisions to make with my starting line-up for this game - which is the kind of headache every manager wants.
BRIAN DEAR is certainly looking forward to the Hammers huge Premier League London derby with Tottenham Hotspur but thought his former side might have benefited had the game been away from home.