Wayne Rooney is also likely to start and will be hoping for warm welcome after securing legendary status at the club where he became record goal scorer.
"I think that Romelu has a better team than Zlatan had", Mourinho explained. This is not the case.
Marouane Fellaini, who replaced Pogba against Basel and scored the opening goal in the 3-0 success, is another option to come in against his former side, along with club captain Michael Carrick.
Written off by many upon switching Paris St Germain for Old Trafford last summer, the veteran striker silenced the doubters by netting 28 goals in his maiden campaign in English football. Despite the fact that The Toffees were one of the most active teams in the transfer market this summer, the results haven't been there for Ronald Koeman's men.
"He has nothing to prove, of course not".
"He's one of the players who needs to react and bring the level of the players we expect from players like Wayne".
Lukaku, meanwhile, should get the nod when United go up against his old club Everton (4pm). In three games at home this term, United have three wins, nine goals scored, and none conceded. He is playing well, there is a good relationship between the way our striker and the way the team plays.
Doom for Nintendo Switch compared to Sony's PlayStation 4
In addition to the announcement, we also saw some gameplay screenshots of DOOM Nintendo Switch version. Wolfenstein II The New Order will hit the PS4, Xbox One and PC on October 27th.
It hasn't been completely straight forward for Mourinho and his preparation has been disrupted by a hamstring injury to Paul Pogba.
"He is injured and he can not play on Sunday", the manager told us.
Mourinho added on MUTV: "That is an opportunity for others and the others are ready to get that opportunity, and to perform".
Both Luke Shaw and Marcos Rojo have been on the treatment table for some time, and it seems that when it comes to Shaw at least, Mourinho is hopeful he can be back in contention for a place soon.
When speaking about the game, Mourinho acknowledged that Sunday's match will be a highly competitive game, as it usually is when the two sides meet.
"The way the team plays I think they have to, when a team doesn't create a lot, doesn't have the ball, when it's just a reactive team, it's more hard".
There is no question Manchester United have started the season on a positive note.
United are unbeaten through four matches and have the best goal differential going into the weekend's slate of fixtures. But The Red Devils will return home, and will try to remain flawless at Old Trafford when they host Everton.