Grande emerged onstage for the One Love Manchester concert Sunday, held at the city's Old Trafford cricket ground.
"And this is so lovely, you guys made that decision, you looked fear right in the face and you said "no we are Manchester and the world is watching".
In-between songs, the 23-year-old tearfully spoke about meeting the victims' families, and she was joined by Miley Cyrus, Take That, Justin Bieber, Little Mix, Coldplay and Pharell Williams amongst others.
Gallagher and Take That hail from Manchester.
Soloist Natasha Seth was joined by Grande and held hands with the pop icon as they both comforted each other during the emotional performance.
Before welcoming Miley to perform Happy, Pharrell said: "You know why I'm bowing, I'm bowing because despite all the things that have been going on in this place, I don't feel or hear or see any fear in this building". "All we feel here tonight is love and positivity".
People thought Will.i.am had made a massive f*ck up when he shouted 'What's up London?' at the One Love concert, but it turns out, he has a very good reason.
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The 23-year-old center was scoreless in the 2016 playoffs and had 10 points in 58 games during the regular season. Jonathan Bernier got thrusted into the spotlight in Game 6, replacing the injured John Gibson in Anaheim's net.
The singer appeared to get emotional as he told those gathered that "God loves you so, so much".
The singer continued to reference London throughout the Black Eyed Peas' set with Ariana Grande, at her fundraising concert on Sunday 4th June, leaving fans bewildered.
'I love you guys so much.
Robbie Williams led the thousands inside the venue in a chorus of: "Manchester, we're strong, we're strong, we're strong".
The One Love Manchester concert raised $US2.6 million in donations in three hours for the victims of the attack.
The One Love Manchester concert has notched up a new record to become the biggest TV show of the year so far - attracting a peak of more than 14 million viewers on Sunday night.
The concert also will be broadcast on more than 130 iHeartRadio stations, and MTV will livestream the event on the website www.onelovemanchester.mtv.com. "But because of you we can now represent through this as a world wide community that we will be ready, we will be fearless we will be great and we will honor our children".
The Manchester concert came the day after attackers targeted the heart of London, killing seven people.