"Our thoughts and prayers are with the families of the two officers killed and with all law enforcement involved in the pursuit of the escaped felons", Powers said.
In Wednesday's news conference, Sills warned the public to be extremely careful if they see the armed escapees and to call 911 immediately.
Authorities had no further signs of the inmates and had no reason to believe they had split up, Sills said.
The sheriff says that their last known whereabouts were a rock quarry in the area where they stole a white F250 Ford truck.
Sills had described the fugitives as violent repeat offenders who are extremely risky, having taken the guards' 9 mm pistols.
Putnam County Sheriff Howard Sills said Wednesday that the two inmates "thoroughly ransacked" a house in Madison, about 25 miles north of where the escape happened, several hours after the guards were killed.
"We showed him the pictures and he said they looked similar, but it probably wasn't them", Malphrus said.
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The truck driver said they looked like they were scoping out the area and planning to steal a vehicle.
"We are asking citizens in this area to be vigilant and report any suspicious activity", the Jasper County Sheriff's Office wrote on its Facebook page around 1 p.m. Both are believed to be armed and unsafe.
The sheriff said the bus is equipped with video, and he's watched it on a cellphone, but couldn't tell which inmate fired the fatal shots at the guards.
The inmates also carjacked a 2004 green Honda Civic 4-door with a Georgia license plate RBJ6601 on Tuesday.
This photo provided by the Elbert County Sheriff's Office taken on October 13, 2015 shows inmate Ricky Dubose. After killing the guards and abandoning the prison bus, Rowe and Dubose carjacked a passerby's auto at gunpoint and ransacked a nearby house for food and clothes.
The deceased security guards were Christopher Monica, a strapping 42-year-old man, and Curtis Billue, 58, an experienced and highly-regarded prison worker.
The union that represents state correction officers is putting $15,000 toward the reward for the capture of two Georgia inmates who allegedly killed two guards and escaped from a prison bus in that state. Both of them have been convicted for the armed robbery case. He was serving a 20-year sentence for armed robbery and assault. "Sgt. Monica leaves behind a wife, two daughters, a community that loves him, people that respected and looked up to him".